BOTOX Serum Reduces Flushing in Some Rosacea Patients - Rosacea Knowledge Forum by Geoffrey Nase PhD

Dr. Geoffrey Nase · #1 (**permalink**) 12th July 2011, 10:59 PM

Injectable BOTOX has been quite effective for some forms of blushing and flushing, especially to heat which is triggered by the release of acetylcholine... and BOTOX blocks that for 5 to 8 months. The main problem relates to the side effects such as "Frozen Face Syndrome"

Now, some anti-aging creams and serums are claiming ingredients that are "Better than Botox" AND some have acutally proven it in head to head studies.

Argireline is the top runner and at high doses will block high levels of acetylcholine responsible for wrinkles and flushing. And the great thing about this treatment is that it is superficial and only lasts for 24 to 36 hours. So, it's a daily treatment.

Here is an interesting article on this subject:

Hyping a topical cream or serum as better than botox is some claim for any anti aging skin care manufacturer to make.

Around twenty years after the anti aging potential of botox injections was first spotted more and more topical products claim to deliver the same results without the needle.

A better than botox cream or serum is essentially a ‘line relaxer’ – just like real botox – they aim to reduce or eliminate your natural expression lines or “motion wrinkles” as derms call them. But do they work and should you buy one?

The active ingredients in many botox like products are peptides or neuropeptides. Peptides are similar to amino acids that exist naturally in the body and target the tiny muscles that cause subtle (and some not so subtle!) expression lines. One of the most well known in recent years is Argireline which is found in the Avon botox equivalent product line and also in DDF Wrinkle Release – among others.

There are a large number of products that use peptides and more recently advanced hexapeptide complexes like the new amazing product from Peter Thomas Roth – FIRMx Growth Factor Extreme Neuropeptide Serum and the cheaper (but less effective) Dermaquest Skin Therapy Peptide Mobilizer.

There are also some botox alternatives that use another emerging ingredient – GABA – the body’s natural muscle relaxant. Freeze 24/7 is one of the most well known of these products and there are others that are equally successful like LiftFusion. Both these product lines claim that they produce instant line relaxing effects – just like botox.

The Dr Brandt skin care line is a real pioneer for GABA – especially Dr Brandt Crease Release which is a market leader in the area (see detailed comments later)

Although GABA on it’s own applied topically would not have any effect at all on the underlying muscles, skin care formulators claim that it works because it is combined with a range of other highly active anti aging ingredients. For instance in the LiftFusion product GABA is combined with a cocktail of peptides which the makers call M-tox – probably to get us to think it is just like botox.

-- Not a cure, but it might help many reduce the intensity and duration of facial flushing and blushing.

__

Dr. Geoffrey Nase · #2 (**permalink**) 5th August 2011, 04:18 AM

Quote:

Originally Posted by Dr. Geoffrey Nase

Injectable BOTOX has been quite effective for some forms of blushing and flushing, especially to heat which is triggered by the release of acetylcholine... and BOTOX blocks that for 5 to 8 months. The main problem relates to the side effects such as "Frozen Face Syndrome"

Now, some anti-aging creams and serums are claiming ingredients that are "Better than Botox" AND some have acutally proven it in head to head studies.

Argireline is the top runner and at high doses will block high levels of acetylcholine responsible for wrinkles and flushing. And the great thing about this treatment is that it is superficial and only lasts for 24 to 36 hours. So, it's a daily treatment.

Here is an interesting article on this subject:

Hyping a topical cream or serum as better than botox is some claim for any anti aging skin care manufacturer to make.

Around twenty years after the anti aging potential of botox injections was first spotted more and more topical products claim to deliver the same results without the needle.

A better than botox cream or serum is essentially a ‘line relaxer’ – just like real botox – they aim to reduce or eliminate your natural expression lines or “motion wrinkles” as derms call them. But do they work and should you buy one?

The active ingredients in many botox like products are peptides or neuropeptides. Peptides are similar to amino acids that exist naturally in the body and target the tiny muscles that cause subtle (and some not so subtle!) expression lines. One of the most well known in recent years is Argireline which is found in the Avon botox equivalent product line and also in DDF Wrinkle Release – among others.

There are a large number of products that use peptides and more recently advanced hexapeptide complexes like the new amazing product from Peter Thomas Roth – FIRMx Growth Factor Extreme Neuropeptide Serum and the cheaper (but less effective) Dermaquest Skin Therapy Peptide Mobilizer.

There are also some botox alternatives that use another emerging ingredient – GABA – the body’s natural muscle relaxant. Freeze 24/7 is one of the most well known of these products and there are others that are equally successful like LiftFusion. Both these product lines claim that they produce instant line relaxing effects – just like botox.

The Dr Brandt skin care line is a real pioneer for GABA – especially Dr Brandt Crease Release which is a market leader in the area (see detailed comments later)

Although GABA on it’s own applied topically would not have any effect at all on the underlying muscles, skin care formulators claim that it works because it is combined with a range of other highly active anti aging ingredients. For instance in the LiftFusion product GABA is combined with a cocktail of peptides which the makers call M-tox – probably to get us to think it is just like botox.

-- Not a cure, but it might help many reduce the intensity and duration of facial flushing and blushing.

__

Argireline polimotyl hexapeptide may penetrate skin deeper and be more effective. Now available in the better anti-wrinkle creams.... $200 and up though

__

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