Every week more literature comes to light regarding the effect of alpha lipoic acid (ALA) on inflammation in muscles and skin -- including inflammatory skin disorders.

ALA has been shown to decrease three important inflammatory enzymes and genes that are central to rosacea: Neutrophils, intracellular adhesion molecules (ICAM-1) and NFkB (the master inflammatory switch in facial skin). While oral ALA has never been directly tested against rosacea symptoms, its mechanism of action shows great promise for skin inflammation. Below is an excerpt of the latest findings supporting these statements:


ALPHA-LIPOIC ACID MAY HELP REDUCE INFLAMMATION
The incidence of inflammatory diseases such as arthritis increases with age. Free radicals promote inflammatory reactions, which antioxidants have been successful at diminishing. Scientists recently stimulated the inflammatory response of white blood cells, resulting in an increase of Intracellular Adhesion Molecule 1 (ICAM-1), which encourages white blood cells to stick to other cells, thereby inflaming tissues. Alpha-lipoic acid, a potent antioxidant, was then added to the mix. Researchers said the acid reduced the activity of ICAM-1 to levels in normal, un-stimulated cells in a dose-dependent manner. It also lowered the activity of NFkB (NFkB can increase the activity of genes responsible for inflammation). According to the study, these changes suggest that alpha-lipoic acid may help reduce the effects of inflammatory diseases such a rheumatoid arthritis and psoriasis.

Purchasing the correct form of ALA is central to its overall action. This can be extremely confusing for most people. Please visit the following link for the most effective oral ALA products: Oral ALA products for rosacea

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Best,
Geoffrey

Dr. Geoffrey Nase
Ph.D: Neuro-Vascular Physiologist

Email: drnase1000@hotmail.com
Bibliography: http://drnase.com

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Very interesting. Didn't you inform us that Na-RALA ( R-lipoic acid) would be good to add as a supplement?? Is there a difference between the two?

How much Alpha Lipoic Acid should we take daily?

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Doug