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4th December 2009, 07:10 AM
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Will Sansrosa use Sol-Gel Technology?
After interviews with Galderma reps. it seems like they are looking into time release delivery systems. This is a good thing as Galderma is notorious for putting active ingredients into lousy bases filled with mineral oil and propylene glycol.
Will Sol-Gel technology be out in time for them to trial it and will they use it? They also have another great alternative called Q-somes. You can fill Q-somes with the active ingredient and trhey gently carry the active ingredient (and alpha adrenergic agonist) deep into the layers of the dermis and release them slowly into the skin over 8 hours. Lets hope they combine this excellent active ingredient with top-notch inactive delivery systems. Geoffrey
__________________
_ Best, Geoffrey Dr. Geoffrey Nase Ph.D: Neuro-Vascular Physiologist Email: drnase1000@hotmail.com Bibliography: http://drnase.com All posts are for informational purposes only. Please visit our Home Page to view our Medical Disclaimer. 
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14th December 2009, 10:37 AM
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Dr Nase,
it always lifts my spirit when I read about Sansrosa. I have much so hope it will help me. Are you able to give a rough estimate of the launch of Sansrosa? Do you think we still have to wait years? Thanks, Barbara
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23rd December 2009, 12:48 PM
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24th December 2009, 02:48 PM
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Hi Barb, I think this product will come to fruition. They just need to decide what strength to use and then measure blood pressure to make sure too much is not absorbed. The biggest time gap was switching companies. Once you reach phase III studies, things move fast. _
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_ Best, Geoffrey Dr. Geoffrey Nase Ph.D: Neuro-Vascular Physiologist Email: drnase1000@hotmail.com Bibliography: http://drnase.com All posts are for informational purposes only. Please visit our Home Page to view our Medical Disclaimer.
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5th January 2010, 08:07 AM
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Barbara, We should get updates from the company on Phase III testing within two months. I will forward any correspondence that I receive. _
__________________
_ Best, Geoffrey Dr. Geoffrey Nase Ph.D: Neuro-Vascular Physiologist Email: drnase1000@hotmail.com Bibliography: http://drnase.com All posts are for informational purposes only. Please visit our Home Page to view our Medical Disclaimer.
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7th January 2010, 02:00 PM
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Dr. Nase,
thanks, I'm looking forward to any news about the development of Sansrosa. Again Thank you for all your time and effort you are putting in this board. The Dose-Finding-Study (Phase II) of Sansrosa has been completed now. Dose-Finding Study of CD07805/47 Topical Gel in Subjects With Erythematotelangiectatic Rosacea - Full Text View - ClinicalTrials.gov Barbara
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10th January 2010, 05:43 AM
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Good stuff Barbara. It takes a while to publish, so they are full tilt into Phase III trials. Time release, the right concentration and the proper base could make for the best topical yet. _
__________________
_ Best, Geoffrey Dr. Geoffrey Nase Ph.D: Neuro-Vascular Physiologist Email: drnase1000@hotmail.com Bibliography: http://drnase.com All posts are for informational purposes only. Please visit our Home Page to view our Medical Disclaimer.
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