Rosacea Supplements - Rosacea Knowledge Forum by Dr. Geoffrey Nase - Advancements in Rosacea Treatments, Rosacea Research, Rosacea News & Rosadyn Therapy

Del Griffith · #1 (**permalink**) 20th February 2010, 04:43 PM

Dr. Nase,

I plan on giving Rosadyn another go soon. In the mean time, I was wondering if you or anyone on this forum for that matter, would offer their opinion?

What are the absolute "must have" supplements for rosacea? Supplements that you think every rosacea sufferer needs to be taking everyday.

I feel like I am doing myself a disservice by not taking at least a few supplements everyday for my skin.

Your thoughts?

Dr. Geoffrey Nase · #2 (**permalink**) 22nd February 2010, 09:56 PM

Quote:

Originally Posted by Del Griffith

Dr. Nase,

I plan on giving Rosadyn another go soon. In the mean time, I was wondering if you or anyone on this forum for that matter, would offer their opinion?

What are the absolute "must have" supplements for rosacea? Supplements that you think every rosacea sufferer needs to be taking everyday.

I feel like I am doing myself a disservice by not taking at least a few supplements everyday for my skin.

Your thoughts?

Hi Del,

Thank you for your input. Here is my list of "must have" supplements:

1. Buffered Vitamin C with bioflavanoid complex - 1,000 to 3,000 mgs
2. Phosphatidylserine - 100 mgs per day to heal and stabilize cell membranes of blood vessels and skin cells
3. Bioenhanced R-Lipoic Acid - This is one of the few antioxidants that scavenges free radicals in the aqueous phase surrounding the cells, and the lipid phase that makes up the plasma membrane.
4. BroccoRaphanin - This is one of the hottest ingredients for blood vessel repair and strength..... we purchase it in bulk, so you cant find a better deal on this than rosadyn. They sell this product by itself for half the price of our Rosadyn.
5. Billberry extract with 25% anthocyandins

This is a great starting place.

_

JamieK · #3 (**permalink**) 1st March 2010, 01:04 PM

Dr. Nase, is there a reason why you recommend Bilberry Extract over Grape Seed Extract which has a higher proanthocyanidin level?

Also, what do you think about the supplement Glisodin which is supposed to increase levels of glutathione, SOD and catalase? Any benefit for rosacea sufferers?

Thanks.

Dr. Geoffrey Nase · #4 (**permalink**) 4th March 2010, 08:09 AM

Quote:

Originally Posted by JamieK

Dr. Nase, is there a reason why you recommend Bilberry Extract over Grape Seed Extract which has a higher proanthocyanidin level?

Also, what do you think about the supplement Glisodin which is supposed to increase levels of glutathione, SOD and catalase? Any benefit for rosacea sufferers?

Thanks.

Hi Jamie,

Good question. You can get a better bioactive proanthocyandin complex out of pine bark extract (pycnogenol) than you can via grape seed extract.... although there is heated debate due to the sales force. For us, Pine Bark is better for the blood vessels..... for hypertensive patients with plaque build up on their arteries, grape seed extract is the number one choice.

Also. the bilberry contains anthocyandins which are a different class of molecules than proanthocyandins. Anthocyandins complement pycnogenol quite well.

I love GliSODin. A great free radical scavenger and it gives us natural protection from sunburn. I believe 250 mgs is approximate to an SPF of 18 to 20. This product allows me to go outside and play basketball and tan slowly without the sunburn affect.

GliSODin also stimulates our primary natural antioxidant enzyme glutathione.... which does about everything. However, now you can purchase GliSODin with Glutathiohe (reduced) for an extra kick. I believe Vitacost.com has some excellent brands.

Dont forget the R-Alpha Lipoic Acid Bioenhanced. Do NOT purchase plain alpha lipoic acid as 70% is not active in the body. Do not purchase R Lipoic Acid if it is not "Bioehanced or Stabilized" as R-lipoic acid is not stable and will oxidize upon swallowing.

If you want to review the best forms of R-Lipoic Acid and some newer cutting edge reduced forms Dihydrolipoic acid in gel visit the leaders in the field Gernova.

R-ALA Bioenhanced is excellent because it works inside and outside the cells and it is one of the best products for removing alll the inflammatory adhesions of blood vessels and skin cells. You might not wake up one morning and say, WOW, but you do need to address the permanent celll adhesion molecules that are central to rosacea inflammation: Cell Adhesion 1 (CAM1), Vascular Celll Adhesion Molecule (VCAM), Endothelial Cell Adhesion Molecule (ECAM), etc.

_

JamieK · #5 (**permalink**) 4th March 2010, 06:10 PM

Thank you for clearing that up. I think Pycnogenol also increases levels of antioxidant enzymes if I'm not mistaken and protects against sun damage.

I'd love to try lipoic acid but I've read some things about it that scare me a little bit. On the Lef.org forum, there was a discussion on ALA and some people were saying that they developped hair problems (hair falling out and gray hairs popping up) after taking ALA. I also read something on another forum where a woman took 100mg of ALA after reading Dr. Perricone's book and she also developped hair problems. Turns out it was because of a biotin deficiency because of the ALA. She tried taking extra biotin but still had hair issues which resolved when she stopped taking the ALA.

Maybe R ALA is different?

Dr. Geoffrey Nase · #6 (**permalink**) 16th March 2010, 10:46 PM

Quote:

Originally Posted by JamieK

Thank you for clearing that up. I think Pycnogenol also increases levels of antioxidant enzymes if I'm not mistaken and protects against sun damage.

I'd love to try lipoic acid but I've read some things about it that scare me a little bit. On the Lef.org forum, there was a discussion on ALA and some people were saying that they developped hair problems (hair falling out and gray hairs popping up) after taking ALA. I also read something on another forum where a woman took 100mg of ALA after reading Dr. Perricone's book and she also developped hair problems. Turns out it was because of a biotin deficiency because of the ALA. She tried taking extra biotin but still had hair issues which resolved when she stopped taking the ALA.

Maybe R ALA is different?

Jamie,

Im a big fan of alpha lipoic acid (more specifically, the stabilized bioenhanced r-lipoic by GeroNova the premiere lipoic acid pharmaceutical company). Remember to take Internet information with a grain of salt. Alpha lipoic acid should not affect hair growth or color in any way. In fact, by blocking hydroxyl radicals it should increase hair growth speed and decrease greying.... look at the latest studies on grey hair and you will find that it is primarily caused by peroxide radicals... it bleaches the hair follicle from the inside out.

ALA is a great supplement for rosacea as it acts in the water phase outside cells and the lipid phase inside cell membranes. It also decreases many types of cell adhesion molecules (ICAMS) that are central to rosacea.

If you want to purchase one of the best all around antioxidants and one that impacts rosacea go to GeroNova's site and see how advanced they are.... a bit pricey, but worth a trial.

GeroNova Products Overview | GeroNova

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Dr. Geoffrey Nase · #7 (**permalink**) 18th March 2010, 11:51 PM

Jamie,

For blood vessel protection against free radicals, inflammation, glucose and insulin, I highly recommend benfotiamine. Benfotiamine protects blood vessels from breaking down at the cellular level and 'cross linking'.

You can read quite a bit about its vasculoprotective abilities at Diabetic Nutritional Supplement, Neuropathy Treatment, Enzyme Transketolase - Benfotiamine.Net. This is especially important for rosacea sufferers who have diabetes, prediabetes, hypertension or are insulin resistant.

150 mgs per day for normal cases
300 mgs for those with secondary metabolic disorders as vascular damage is more aggressive.

_

Nadiko · #8 (**permalink**) 16th April 2010, 08:17 AM

Hi Del,

I think the Rosadyn is the best thing I've run across. Though my papules don't seem to be improved my flushing and blushing seems to be a thing of the past. I also have faired much better this winter in regulating my body temperature going from hot to cold and visa versa. Glad to hear you're trying it again. Just remember like all things... it takes a little while to kick in. I try to take 2 capsules twice a day myself. I have a friend who is a former nurse and a nutritionist who took a look at the product. She said it would be great for vascular disorders in general and to continue with it. So, I'm going to be ordering again.

Best wishes to you as you improve your general health & in turn, your rosacea!

Dr. Geoffrey Nase · #9 (**permalink**) 18th April 2010, 04:47 AM

Quote:

Originally Posted by Nadiko

Hi Del,

I think the Rosadyn is the best thing I've run across. Though my papules don't seem to be improved my flushing and blushing seems to be a thing of the past. I also have faired much better this winter in regulating my body temperature going from hot to cold and visa versa. Glad to hear you're trying it again. Just remember like all things... it takes a little while to kick in. I try to take 2 capsules twice a day myself. I have a friend who is a former nurse and a nutritionist who took a look at the product. She said it would be great for vascular disorders in general and to continue with it. So, I'm going to be ordering again.

Best wishes to you as you improve your general health & in turn, your rosacea!

Nadiko,

I am glad to hear your positive response to Rosadyn. Many have noted increased effectiveness on extra strength Rosadyn (e.g 2 capsules twice a day). The papules might respond better if you increase your dose of L-Optizinc with copper sebacate (very inexpensive by NOW Foods and the best form). We have included a therapeutic dose of Optizinc in Rosadyn, but some rosacea clinical studies increase the zinc dose up to 300 mgs daily for 3 to 6 months (safely) and then wean back down to a maintenance dose. Zinc is just as good, if not better at the treatment of papules and pustules when compared to oral antibiotics.

Very perceptive on the affect of Rosadyn on vascular disorders. As a Microvascular Physiologist, I included 7 ingredients that should have an excellent effect on vascular disorders such as hypertension, diabetes, stroke and vascular plaque formation. Also excellent post aerobic and anaerobic exercise as it quenches free radicals that are produced within blood vessel walls and speeds up recovery.

Dr. Geoffrey Nase · #10 (**permalink**) 18th April 2010, 05:32 AM

Quote:

Originally Posted by Dr. Nase

Nadiko,

I am glad to hear your positive response to Rosadyn. Many have noted increased effectiveness on extra strength Rosadyn (e.g 2 capsules twice a day). The papules might respond better if you increase your dose of L-Optizinc with copper sebacate (very inexpensive by NOW Foods and the best form). We have included a therapeutic dose of Optizinc in Rosadyn, but some rosacea clinical studies increase the zinc dose up to 300 mgs daily for 3 to 6 months (safely) and then wean back down to a maintenance dose. Zinc is just as good, if not better at the treatment of papules and pustules when compared to oral antibiotics.

Very perceptive on the affect of Rosadyn on vascular disorders. As a Microvascular Physiologist, I included 7 ingredients that should have an excellent effect on vascular disorders such as hypertension, diabetes, stroke and vascular plaque formation. Also excellent post aerobic and anaerobic exercise as it quenches free radicals that are produced within blood vessel walls and speeds up recovery.

Nadiko,

You could probably take up to three 30 mg supplements of L Optizinc daily... in addition to the Rosadyn. See abstract and photo below. They use 300 mgs without side effects for several months. BTW, for clinical purposes, Zinc Sulfate and Zinc Oxide are terrible zinc supplements as the absorption and bioavailabliity are extremely poor. Always choose a "chelated" form which means its bound to an amino acid and thus slips through the amino acid transporters in the intestine via piggy back. The best amino acid to chelate to zinc is methionine.... "OptiZinc".

Int J Dermatol. 2006 Jul;45(7):857-61.

Oral zinc sulfate in the treatment of rosacea: a double-blind, placebo-controlled study.

Sharquie KE, Najim RA, Al-Salman HN.

Abstract

BACKGROUND: Rosacea is a skin problem not uncommonly encountered world-wide. There is a need for an effective and well-tolerated treatment for this disease.

OBJECTIVE: To evaluate the efficacy and side-effects of zinc sulfate in rosacea in a randomized, controlled, double-blind trial.

PATIENTS AND METHODS: Patients with rosacea who attended the outpatient Clinic of Dermatology and Venereology in Baghdad Teaching Hospital were recruited into this study between October 2002 and August 2004. A disease severity score was calculated for each patient. The patients were randomly allocated to receive either zinc sulfate 100 mg or identical placebo capsules three times per day. Zinc sulfate and placebo capsules were given in a double-blind manner. Following 3 months of starting the treatment, the patients crossed over, i.e. patients on placebo crossed over to zinc sulfate and those on zinc sulfate crossed over to placebo.

RESULTS: Twenty-five patients with rosacea were included in this study: 16 (64%) females and nine (36%) males. Nineteen patients completed the study: 11 (58%) females and eight (42%) males. Patient age ranged from 21 to 64 years with a mean +/- SD of 48.2 +/- 9.3 years. Duration of the disease ranged from 1 to 14 years with a mean +/- SD of 4.4 +/- 3.2 years. In the group started on zinc sulfate, the score before therapy ranged from 5 to 11 with a mean +/- SD of 8 +/- 2.0. The mean started to decrease directly after the first month of therapy with zinc sulfate to a significantly lower level. After shifting to placebo treatment, the mean started to rise gradually in the fifth month but remained significantly lower than the levels before therapy. In the group started on placebo, the score before therapy ranged from 5 to 9 with a mean +/- SD of 7 +/- 1.3. The mean remained high in the first 3 months of therapy while the patients were on placebo. After shifting to zinc sulfate, the mean started to decrease after the fourth month to significantly low levels. No important side-effects were reported apart from mild gastric upset in three (12%) patients on zinc sulfate.

CONCLUSION: Zinc sulfate was found to be a good option in the treatment of rosacea, as it was safe, effective and lacking important side-effects.

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