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Old 20th April 2010, 11:31 PM
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Thumbs down NEVER exceed 10mgs of accutane per day

Rosacea skin is not meant to absorb more than 10 mgs per day of accutane. Contrary to what general Dermatologists suggest, 20 mgs every other day does not equal 10 mgs per day. Your body and skin is bombarded by 20 mgs within 4 hours of taking the capsule.

10 mgs per day is great
5 mgs per day is even better
2.5 mgs is excellent
1.0 mgs (new rambazole - should hit the mark perfectly)

Normal acne patients turn red when they take 20 to 40 mgs per day.

I turned red and burned for one month when my Derm put me on 20 mgs per day. They we went down to 10 mgs and my face became white and it cleared the burning.

In a clinical study of 18 rosacea sufferers with skin inflammation, redness and severe burning, all 18 subjects noted at least a 50% reduction in redness and burning on 10 mgs of accutane. It is still the rosacea treatment of choice... but it's been blacklisted so it will be very hard to find except on online pharmacies (please be careful).
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Old 21st April 2010, 03:37 AM
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Also remember the precautions about laser/IPL treatments when using accutane *at any dose*. I think you have to wait 6 months after completing a course of accutane before having any laser/IPL/PDL/RFL treatments.
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Old 21st April 2010, 10:38 AM
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Would a Dermatologist prescribe the Accutane or should your primary physician?? I checked with a lot of Dermatologist under my plan and many of them dont even perform Tape Tests which is very frustrating. I dont know who to go to in order to know whether my problem is Demodex related or just pimples related to the rosacea that are itchy.
You have mentioned something else called Roxithromycin..Is that like a minocyclin?? I have taken Minocylin years ago and I think that what triggered my stomach issues and have no longer been the same due to the bacteria.
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Old 22nd April 2010, 06:46 AM
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Originally Posted by chanel77 View Post
Would a Dermatologist prescribe the Accutane or should your primary physician?? I checked with a lot of Dermatologist under my plan and many of them dont even perform Tape Tests which is very frustrating. I dont know who to go to in order to know whether my problem is Demodex related or just pimples related to the rosacea that are itchy.
You have mentioned something else called Roxithromycin..Is that like a minocyclin?? I have taken Minocylin years ago and I think that what triggered my stomach issues and have no longer been the same due to the bacteria.


Chanel,

I have no idea why they would not perform a tape test.. its the easiest, least expensive way to see what is going on in the pores. Many would rather take a mid-depth biopsy, but rosacea skin has a tendency to heal incorrectly (hypertrophic or keloid scars), so I would stay away from that.

Roxithromycin is much different than the tetracyclines, but it is stil not a good medication if Demodex play a role.

I would call multiple dermatology offices and ask them how they perform tests to determine if humans are infected with Demodex mites (demodex rosacea). If they connect you to a vet's office you know they were the wrong office for you
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Old 22nd April 2010, 07:14 PM
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Are skin scarpings ok?? Or does it leave scars? I called 4 dermatologists yesterday and tape testing doesnt seem common. Very annoying.
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Old 23rd April 2010, 10:00 AM
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Are skin scarpings ok?? Or does it leave scars? I called 4 dermatologists yesterday and tape testing doesnt seem common. Very annoying.

Chanel,

It looks like most dont perform tape tests or expression testing. The skin scraping should be fine... might leave your skin a little irritated, but it seems that this is now the preferred method for diagnosis.

Br J Dermatol. 2010 Feb 25. [Epub ahead of print]

Comparison of the two techniques for measurement of the density of Demodex folliculorum: standardized skin surface biopsy and direct microscopic examination.

Aşkın U, Seçkin D.


Abstract

Summary Background

In daily dermatological practice, many dermatologists do not include demodicosis in their differential diagnoses, or the diagnosis of demodicosis is frequently masked by other skin diseases such as papulopustular or erythematotelangiectatic rosacea, seborrhoeic dermatitis, perioral dermatitis and contact dermatitis. There are two methods for measurement of the density of Demodex folliculorum (Dd): standardized skin surface biopsy (SSSB) and direct microscopic examination of fresh secretions from sebaceous glands (DME). No study has been reported in the literature comparing the diagnostic value of these two techniques. Objectives To compare the value of the two techniques, SSSB and DME, for the measurement of Dd in patients with suspected demodicosis. Methods Mite density was investigated using SSSB and DME in 37 patients with facial skin lesions suggesting demodicosis. Two samples, one for SSSB and one for DME, were obtained from a cheek lesion of each patient.

Results Twenty-three (62%) patients were diagnosed with demodicosis according to their clinical manifestations combined with a high Dd (Dd > 5 mites cm(-2)) with SSSB and/or DME. In all the patients, the mean Dd measured with SSSB was higher than that with DME (22.9 +/- 5.9 and 2.2 +/- 0.8, respectively; P = 0.001). Also, among the 23 patients with demodicosis, the mean Dd measured using SSSB was higher than the mean Dd with DME (36.5 +/- 8.3 and 3.4 +/- 1.2, respectively; P = 0.0001).

Conclusions We recommend the use of SSSB for the measurement of Dd as more patients with demodicosis can be diagnosed with this method compared with the DME method.

PMID: 20199545 [PubMed - as supplied by publisher]
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Old 23rd April 2010, 03:58 PM
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what is a tape test? Do you believe mites play a role in rosacea?
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Old 23rd April 2010, 06:02 PM
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how does accutane reduce the redness?
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