IMPORTANT:
A Unifying Theory of Rosacea Pathophysiology
The Role of Neutrophils. The intimate relationship between the vasculature and the immune system, as well as the success of anti-inflammatory agents in the treatment of rosacea, suggests that inflammatory cells such as neutrophils, and other inflammatory mediators, are key pathophysiologic factors in the development of rosacea[21] (Figure 6). The stigmata of rosacea may be manifestations of an inflammatory process: neutrophilic dermatosis.[21] Therefore, pharmacologic modulation of neutrophilic function is critical to the resolution of rosacea.[22]
Excellent Link:
http://www.medscape.com/viewarticle/448505_5